Insights into cardioprotection obtained from study of cellular Ca handling in myocardium of true hibernating mammals
نویسندگان
چکیده
Atsuko Yatani, Song-Jung Kim, Raymond K. Kudej, Qian Wang, Christophe Depre, Keiichi Irie, Evangelia G. Kranias, Stephen F. Vatner, and Dorothy E. Vatner Cardiovascular Research Institute and Department of Cell Biology and Molecular Medicine, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, New Jersey 07103; and Department of Pharmacology and Cell Biophysiology, College of Medicine, University of Cincinnati, Cincinnati, Ohio 45267
منابع مشابه
Insights into cardioprotection obtained from study of cellular Ca2+ handling in myocardium of true hibernating mammals.
Mammalian hibernators exhibit remarkable resistance to low body temperature, whereas non-hibernating (NHB) mammals develop ventricular dysfunction and arrhythmias. To investigate this adaptive change, we compared contractile and electrophysiological properties of left ventricular myocytes isolated from hibernating (HB) woodchucks (Marmota monax) and control NHB woodchucks. The major findings of...
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